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  • Product Description

Leptin, a 16 k-Da protein, has been shown to have roles in diverse physiological processes, such as regulation of body weight and food intake, immune function, hematopoeisis and reproduction. Hypogonadotropic hypogonadism and infertility are common features in leptin deficient ob/ob mice. Exogenous leptin administration increases testicular and seminal vesicle weight, and elevates sperm counts and restores reproductive capacity in leptin deficient mice. Although the effects of leptin deficiency on reproduction are well recognised, the effect of excess leptin on male reproductive function in non-deficient animals is not clear. Sperm quantity and quality have both been negatively correlated with BMI, and DNA fragmentation Index has been found to correlate significantly with BMI. The factor/s involved in obesity related alterations in reproductive function remains unknown. Since leptinaemia is commonly evident in obese individuals we wondered if leptin could be responsible for the reported negative correlation between BMI and sperm quantity and quality. We therefore examined the effect of exogenous leptin administration on sperm count and sperm morphology in adult normal rats.

Product Specifications
SKU :COC22911
AuthorMohd Nizam Haron,Harbindar Jeet Singh and Hasnan Jaafar
Number of Pages112
Publishing Year2/15/2010
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-28 00:00:00