Medicinal and aromatic plants occupy an important economic position because of the continuous and increased demand for their products from local and foreign markets. Artemisia is one of the most important medicinal plants in this area. It is a plant for the production of anti-malarial, anti-bacterial agents and natural pesticides. Artemisinin, the secondary compounds of interest in the plant is mostly found in the leaves. A number of control measures employed against malaria have their weakness. For instance, some strains of the malaria parasite have developed resistance to traditional treatments using quinine and chloroquine, which were previously effective. WHO has recommended the use of Artemisinin-Based Combination treatments as the first line treatments for multidrug – resistance strains. Field production of Artemisia annua is therefore; recommended as the only commercially viable method to produce artemisinin since the total chemical synthesis of the molecule is complex and uneconomical. This work seeks to find out the effect of organic and inorganic fertilizer application on the growth and yield of artemisia.