Even after investing a lot of time and clinical skill a definitive movement of teeth during and after processing has long been observed which lead to occlusal discrepancies & disturb the harmonious occlusal scheme achieved earlier. Shifting of the teeth can occur as a result of the investing procedures & investing materials. The objective of this study was to evaluate and compare the movement of artificial teeth in two dimensions of space during processing of the waxed-up dentures using two different gypsum materials for investing. Two groups of 15 waxed-up maxillary dentures were processed using two different investing mediums a) dental plaster & b) combination of dental stone core & plaster mold. The artificial teeth movement was measured in the medio-lateral and the antero-posterior directions between predetermined reference points before and after processing with the aid of a traveling microscope. The findings were statistically analyzed using parametric‘t’ tests and ANOVA ‘F’ test. The results indicate that the dental Stone core method is superior in view of the fact that it produces significantly less artificial teeth movement than the conventional method.