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Effects of new onset diabetes and dyslipidemia on the allograft

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

The principal risk factors for cardiovascular mortality posttransplantation are hyperglycemia, hypertriglyceridemia, obesity, and smoking. We assessed the risk factors for new-onset diabetes and dyslipidemia and their effects on the function and histopathologic changes in the allografts at 1 year posttransplantation. In regard to immunosuppressive therapy, new onset diabetes mellitus was significantly more frequent among patients prescribed tacrolimus, whereas subjects who received cyclosporine A showed a significantly higher incidence of dyslipidemia. In regard to allograft function, a significant difference was noted at year 1 after transplantation. When assessing morphologic changes in the kidney, we observed significantly more frequent interstitial fibrosis/tubular atrophy in all 3 groups compared with normal function patients. Our clinical study suggested that at year 1 after transplantation the allograft function is already impaired in the presence of both medical conditions (diabetes and dyslipidemia). However, in regard to morphology, a single condition (diabetes or dyslipidemia) is sufficient to produce histologic changes in the kidney.

Product Specifications
SKU :COC84388
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
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