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Epigenetic Therapy of MHC class I Tumors and Myeloid Neoplasms


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Epigenetic agents such as DNA methyltransferase inhibitors and inhibitors of histone deacetylase are currently used in clinical studies to reverse altered histone modifications and aberrant DNA methylation which can lead to tumor growth. Because epigenetic modifications are functionally equivalent to genetic changes and some have been linked to tumorigenic events, researchers have attempted to identify epigenetic mechanisms that may lead to disease such as cancer. Recent data has shown that the use of these agents positively influence the induction of down-modulated immunoactive(e.g. MHC class I or II), co-stimulatory and adhesive molecules on tumor cells, cytokine production and the expression of tumor-rejecting antigens. Therefore, the anti-tumor therapeutic potential of these agents is promising and are welcomed additions to the medicinal arsenal currently used in the fight against cancer.

Product Specifications
SKU :COC87258
AuthorJasper Manning
Number of Pages92
Publishing Year2013-06-17T00:00:00.000
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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