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EPS8 and E3B1 Proteins in Human Cancers

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

EPS8 protein has been known to be involved in the signaling pathway of different cancers, and protein E3B1 is considered to be a downstream target for EPS8. By participating in the formation of various macromolecular complexes, E3B1 has been found to mediate a number of signal pathways related to cancer cell proliferation. We carried out expression analysis studies of EPS8 in esophageal, stomach and lung carcinomas, and observed increased expression of the protein in esophageal and stomach cancers, whereas, the observed expression of this protein in lung cancers was fairly equal. Likewise, the expression of E3B1 was studied in esophageal, breast, gastro-eophageal junction, stomach and colorectal cancers, and observed a consistent decrease in all these cancers except for breast cancers where no change in expression was observed. Our data supports a novel cancer-specific role of the two proteins in the mentioned cancers and suggest EPS8 and E3B1 could have a pivotal role in the progression of these cancers.

Product Specifications
SKU :COC97895
AuthorRafia Anjum Baba and Firdous Ahmad Khanday
LanguageEnglish
BindingPaperback
Number of Pages116
Publishing Year2011-12-28T00:00:00.000
ISBN978-3847325086
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00