In the Present book Chapter I is an introductory one. It contains the general introduction about the problem of heteroscedasticity. Chapter II describes some aspects of linear models with their inferential problems. It deals with some basic statistical results about Gauss-Markov linear model besides the restricted least squares estimation and its application to the tests of general linear hypotheses. Chapter III presents a brief review on the existing estimation methods for linear models under the various specifications of heteroscedastic variances. Chapter IV deals with the analysis and examination of different types of residuals with their applications in the regression analysis. It also contains the restricted residuals in ‘Seemingly Unrelated Regression’ (SUR) systems. Chapter V proposes some new estimation procedures for linear models under heteroscedasticity. Chapter VI depicts the conclusions .Several references articles regarding the estimation for linear models under heteroscedasticity have been presented under a title “BIBLIOGRAPHY”.