The issue of antimicrobial drugs quality and affordability concerns everybody. This is what justifies the World Health organization's recommendation for a continuous review of medicines circulating in the world market. The preponderance of unsubstantiated claim of Nigerians that, antimicrobials from foreign Industries appeared to have an edge over their local counterparts qualitatively has called for a vigorous scientific attention. This book therefore,present a comparative study on the quality, potency, availability, affordability and sources of local and foreign drugs. This book would serve as a guide to the researchers in the field of Chemistry, Microbiology, Pharmaceutical Sciences and Biochemistry. The book would also be useful to Medical Doctors, Pharmacies, Pharmaceutical industries and drug policy makers.