Call Us 080-41656200 (Mon-Sat: 10AM-8PM)
Free Shipping above Rs. 1499
Cash On Delivery*

Exploring the reactivity of the S-cis-methylaziridine aldehyde

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

 

Check Your Delivery Options

 
Rs. 2,675

Availability: In stock

 
  • Product Description
 

This project examined the utility and reactivity of S-cis-methylaziridine aldehyde, developed in Dr. Yudin’s lab, in peptide macrocyclization. Much of my work entailed finding more efficient chemoselective routes that produce high diastereoselectivity, or, in other words, one product is formed in excess over another. In place of the trans configuration of the aziridine aldehyde its cis congener was used in an Ugi four component condensation. The use of S-cis-methyl aziridine aldehyde, tert-butyl isocyanide and proline, either the D or L enantiomer, produced a single diastereomer. These preliminary results showed that using the cis configuration of the aziridine aldehyde was more effective than its trans congener. Furthermore, it provided further insight into the mechanism involved in peptide macrocyclization.

Product Specifications
SKU :COC61147
AuthorGenevieve Canzonieri
LanguageEnglish
BindingPaperback
Number of Pages60
Publishing Year28.08.2014
ISBN9783659594458
Edition1 st
Book TypeChemistry
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-05 00:00:00
0 Review(s)