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Formulation and Characterization of Ranitidine Hydrochloride

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

prepare and evaluate mucoadhesive drug delivery system of Ranitidine hydrochloride tablet using hydrophilic polymers in order to reduce dose frequency to match the initial release of the drug with the conventional dosage form. The formulation was designed adopting optimization technique, which helps in setting up experiments in such a manner that the information is obtained as efficiently and precisely as possible. Initially, considering buoyancy as the main criteria, blank tablets were compressed for different formulae with various polymers HPMC K 15 M, HPMC K 100 M, Carbopol 934. The tablets were prepared by direct compression method and evaluated for Ranitdine content, in vitro release profile and buoyancy. The dissolution study was carried out in simulated gastric fluid using USP dissolution test apparatus employing paddle stirrer.. This indicates the suitability of the technique chosen for the present dosage form.

Product Specifications
SKU :COC31091
AuthorAshok Asati,Sofiya Verma and Sandhya Chaurasia
LanguageEnglish
BindingPaperback
Number of Pages140
Publishing Year7/24/2012
ISBN978-3659195679
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00