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Formulation And Evaluation Of Celecoxib Gel


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Drug delivery through the skin has been a promising concept. Transdermal gel preparations are intended for superficial skin application, mucosal surfaces for local action or skin penetration of medicament or for their soothing or protective action. NSAID’s are having excellent anti-inflammatory and analgesic activity but NSAID’s produces various adverse effects and to avoid this alternate routes of administration have been tried. The aim of this study was to develop suitable transdermal gel formulations of celecoxib using various gelling agent with and without permeation enhancers, which would attenuate the gastrointestinal related toxicities associated with oral administration Celecoxib is a highly selective COX-2 inhibitor. In the present study gel with different concentrations of carbapol, sodium alginate and sodium CMC were prepared. Gels were subjected for various evaluation tests. The gel formulation consisting of 7.5% w/w sodium alginate with DMSO found to be suitable for topical application based on in vitro evaluation.

Product Specifications
SKU :COC31598
AuthorPreeti Karade,Satish Bhise and Rohit Shah
Number of Pages76
Publishing Year11/21/2012
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00