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Formulation and Evaluation of Deltiazem HCl Microspheres

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

The goal in designing sustained release is reduce the frequency of dosing or to increase the effectiveness of the drug by localization at the site of action, reducing the dose required or providing the uniform drug delivery. The use of controlled release (CR) formulations offers many potential advantages such as, sustained blood levels attenuation of adverse effects and improved patient’s compliance. It is important especially in the case of antihypertensive agents, to maintain constant blood levels, as other wise, dose dumping may cause hypo tension and sub-therapeutical levels may cause hypertension. The objectives of the present study was to Develop sustained release DTZ microsphere by using different drug-polymer ratio, in vitro characterization of DTZ, maintain more uniform drug plasma concentration, reduce dosing frequency, avoidance of night time dosing, to estimate drug release profile of the formulations, to choose the best formulation(s) based on the above evaluations and finally to subject the most satisfactory formulation(s) to accelerated stability studies.

Product Specifications
SKU :COC31443
AuthorMaizbha Uddin Ahmed
LanguageEnglish
BindingPaperback
Number of Pages96
Publishing Year8/14/2012
ISBN978-3844327397
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00