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Formulation and Evaluation of Gastroretentive Drug Delivery System


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Certain drugs having poor solubility, degradation in the alkaline pH, absorbed from the proximal part of Gastrointestinal Tract and causes irritation in the stomach. Due to this reason, drug should not achieve 100% bioavailability. To overcome these, Gastroretentive drug delivery system is a promising approach for achieving prolonged and predictable drug delivery profile. Floating drug delivery is an attempt which has been made to retained the drug in the stomach as a way of increasing retention time. Such type of novel drug delivery reduces the dosing frequency which is patient compliant and delivers active entity directly to the site of action. This book therefore provides formulation method for sustained release floating tablet by using hydrophilic and hydrophobic polymers by applying factorial design and this formulations are characterized by different In vitro evaluation tests and performed In vivo evaluation on human volunteers by X-Ray studies.

Product Specifications
SKU :COC94463
AuthorIndrayani Raut,D.D. Chougule and S.A. Bandgar
Number of Pages136
Publishing Year2011-02-06T00:00:00.000
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-14 00:00:00