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Formulation And Evaluation Of Soft Gelatin Capsule Of Nifedipine


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  • Product Description

Capsule dosage form is most convenient and relevant dosage form. Soft gels are becoming a popular dosage form for the administration of liquids, suspensions, pastes and dry powders. Soft gels are easy to swallow and have the ability to mask odors and unpleasant taste. They have an elegant appearance, readily dissolve in the gastric juices of the digestive tract and they may enhance the bioavailability of the active ingredients. Nifedipine, a calcium-channel blocking agent, is widely used in the treatment of angina pectoris and systemic hypertension. Half life of the drug is comparatively short 2 hours and Nifedipine is completely insoluble in water. Therefore, it has been generally accepted that soft gelatin capsule (Softgels) formulations are most efficient for routine hypertension therapy with Nifedipine. The main objective of the study was to formulate and evaluate soft gelatin capsule dosage form of Nifedipine used in the treatment of hypertension using oily polymers like propylene glycol and PEG 400 to enhance the solubility of Nifedipine.

Product Specifications
SKU :COC84949
AuthorNaisarg Pujara and Ramesh Parmar
Number of Pages76
Publishing Year2013-02-03T00:00:00.000
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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