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Formulation and Evalution of Mucoadhesive Nanosuspension for Ulcer

 

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  • Product Description
 

For most of the industry’s existence, pharmaceuticals have preliminary consisted of simple, fast-acting chemical compounds that are dispensed orally or as injectables. During the last three decades, however, formulations that control the rate and target specific area of the body for treatment have become increasingly common. Nowadays, nanosuspension technology with mucoadhesive principle comes into front for achieving to increased uptake and accumulation of drug in affected region of targeted organ. In the present study, preparation of nanosuspension for famotidine and curcumin by solvent evaporation technique as well as media milling technique using stabilizers was initially adopted. Formulation and process variables were identified based on particle size analysis and in vitro drug release. Optimized nanosuspension was characterized by particle size analysis, zeta potential determination, scanning electron microscopy (SEM). In vivo and ex-vivo study of optimized mucoadhesive nanosuspension was performed using rat stomach and compared with marketed suspension for healing of peptic ulcer.

Product Specifications
SKU :COC31122
AuthorDhaval Patel and Patel Jayvadan K.
LanguageEnglish
BindingPaperback
Number of Pages160
Publishing Year2012-04-06T00:00:00.000
ISBN978-3659118241
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00
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