Over the last few years, obesity is the major problem of humans regarding their helth. With this boom in obesity problem, here little effort was made to formulate the dosage form containing the anti-obesity drug-Rosuvastatin Calcium Buccal Tablet. Buccal drug delivery avoids the problem of extensive first pass metabolism regarding the Rosuvastatin Calcium which ultimately leads the enhancement in bioavaibility of drug. So, this book therefore provide the information regarding the buccal drug delivery of drug as a potential tool to bypass the extensive first pass metabolism & improve the biovaibility of drug. Analysis of this research work will help the research fellows, as a shed of light on the buccal drug delivery as a route of drug administration for drug candidate having low bioavaibility due to high first pass metabolism.