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Formulation of loxoprofen loaded-microspheres

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres.

Product Specifications
SKU :COC85183
AuthorPalanivel Venkatesan and Kannappan Valliappan
LanguageEnglish
BindingPaperback
Number of Pages220
Publishing Year2013-09-22T00:00:00.000
ISBN9783659436376
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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