Category

share

Functional characterization of prostate tumour cell lines

Functional characterization of prostate tumour cell lines

 

Marketed By :    Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

 
₹ 3,651

Availability: Out of stock

 

Delivery :

5% Cashback on all Orders paid using MobiKwik Wallet T&C

Free Krispy Kreme Voucher on all Orders paid using UltraCash Wallet T&C
Product Out of Stock Subscription

(Notify me when this product is back in stock)

  • Product Description
 

In this work a siRNA screen of around 1500 genes was performed using four different cell lines (VCaP, LAPC-4, RWPE-1, MDA-PCa 2b). Therefore a new method called living cell array was used in order to obtain information about the process of androgenesis in prostate tumour cell lines. This method is based on the principal of the reverse transfection [Sabatini, 2001], where the cells are added to the plate after the transfection reagent has been spotted. The cells on the living cell array were set under stress by the addition of androgen ablated media while the proliferation and apoptosis was measured. Knocked-out genes that caused a significant increase or decrease of the proliferation/apoptosis ratio were collected. It is expected that some of these genes influence the pathway of the androgen receptor and therefore might be relevant for the development of new inhibitors.

Product Specifications
SKU :COC99404
Country of ManufactureIndia
Product BrandNot defined
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18
0 Review(s)