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Gastric Floating Microcapsules of Metformin HCl

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Despite tremendous advancement in the drug delivery, oral route remains the preferred route for drug administration because of low cost therapy and ease of administration leads to higher levels of patient compliance. Metformin HCl, which is an antihyperglycaemic agent widely, used in the management of NIDDM, gives low bioavailability problem due to its site absorption limitations. Although, metformin extended release tablet formulations were well established, but it causes a great fluctuations in plasma drug levels and fail to improve the bioavailability. But microcapsule formulation offer several advantages over other sustained release systems, especially matrix type tablets; as they can be widely distributed throughout the GI tract and produce local high concentration of drug at the absorption site. Henceforth, the designing of floating microcapsules would be a suitable delivery system for metformin with a new choice of an economical, safe and more bioavailable formulation in the management of NIDDM. This book represents a unique attempt to overview the full range of approaches to the design of a dosage form for gastric retention of drug with absorption limitation problems.

Product Specifications
SKU :COC95124
AuthorBipul Nath,LilaKanta Nath and Bhaskar Mazumder
LanguageEnglish
BindingPaperback
Number of Pages56
Publishing Year2011-09-05T00:00:00.000
ISBN978-3845476803
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-14 00:00:00