Similar to the majority of biological molecules, DNA is degraded rapidly in the body. Its encapsulation into a delivery system increases circulation time and permits accumulation of the drug in certain organs. Lipid-based soft nanoparticles have the ability to encapsulate or complex DNA and shuttle it into the cells by overcoming cellular and molecular barriers. The use of state-of-the-art technology for the systematic evaluation of the gene transfer efficiency of the novel nanoparticles leads to the development of in vivo gene delivery systems for topical non-invasive administration. These delivery systems find application in the development of new gene therapy for dermatology, immunology/vaccines and neurodegenerative diseases.
|Author||Ildiko Badea and Marianna Foldvari|
|Number of Pages||240|
|Country of Manufacture||India|
|Product Brand||LAP LAMBERT Academic Publishing|
|Product Packaging Info||Box|
|In The Box||1 Piece|
|Product First Available On ClickOnCare.com||2015-07-31 00:00:00|