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Gene Regulation by Numbers

 

Marketed By :  Südwestdeutscher Verlag für Hochschulschriften   Sold By :  Kamal Books International  
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  • Product Description
 

This thesis is composed of three parts that are presented in a hierarchical order reflecting increasing organization level of the studied system. Gene regulation was studied at the single gene level first, extended to interacting transcriptional units and finally to its role within small regulatory networks. Our approach consists of an iterative experimental-based mathematical modeling based on promoter libraries with synthetic binding site sequences of variable affinities for selected transcriptional activators. We used such libraries to perform in vivo experiments using the yeast Saccharomyces cerevisiae in order to improve our theoretical models. The main goal of the work is the determination of gene system’s intrinsic properties like cooperativity coefficients and binding affinities of transcription factors to DNA regulatory sequences.

Product Specifications
SKU :COC41534
AuthorBuetti-Dinh Antoine
LanguageEnglish
BindingPaperback
Number of Pages228
Publishing Year4/20/2012
ISBN978-3838132884
Edition1 st
Book TypeMathematics & science
Country of ManufactureIndia
Product BrandSüdwestdeutscher Verlag für Hochschulschriften
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-03-08 00:00:00