The electrodeposition of novel materials such as CoNiFeCu multilayer nanowires for Giant Magneto Resistance (GMR)and Bismuth Telluride nanotubes for thermoelectric applications are presented in this work. The nanowire high aspect ratio geometry allows the measurement of GMR with the current applied perpendicular to the plane (CPP) of the multilayers, which has been theoretically identified as being larger than the GMR in the (CIP) configuration (current in plane of multilayers)in thin films. Electrodeposited multilayer CoNiFeCu/Cu nanowires and nanotubes were fabricated by pulsed applied electric potential. The effect of electrolyte concentration on GMR was investigated. The FeSO4, CoSO4 and NiSO4 concentrations were varied to optimize GMR. Nanolayer thicknesses were controlled and varied for commercially viable GMR results. Micro fluidic magnetic nanoparticles sensors based on CoNiFeCu/Cu GMR nanowires were demonstrated. For thermoelectric applications nanotubes of bismuth- telluride (Bi2Te3) were fabricated and their Seebeck coefficients were reported.