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CMV and Vascular Function During Pregnancy


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Human cytomegalovirus (HCMV) is implicated in several vascular diseases through endothelial dysfunction. Most of the research on CMV has focused on either congenital CMV infections or CMV disease in immunocompromised hosts; however, CMV has also been associated with vascular diseases in immunocompetent individuals, including atherosclerosis and the pregnancy-specific disorder preeclampsia. A direct connection between CMV and vascular dysfunction remains unknown. Therefore, in the presence or absence of an active CMV infection, I chose to study the systemic (mesenteric) and uterine vascular responses in intact, isolated arteries from non-pregnant (NP) and late pregnant (LP) mice. Furthermore, I investigated if a maternal CMV infection leads to poor fetal outcomes, independent of a congenital infection. Viral transmission to the fetus does not occur in the mouse, making it a useful model for studying maternal CMV infections.

Product Specifications
SKU :COC26260
AuthorRandi Gombos
Number of Pages356
Publishing Year2012-03-05T00:00:00.000
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00