This research monograph assessed the physicochemical and bacteriological quality of the sampled drinking-water supply framework to detect the health risks that may arise thereof. It also employed a triangulated retrospective study to evaluate the health effect of the drinking-water supply consumption on the student population, and recommended effecient and sustainable management system to assure the short and long term health of the consumers. It revealed that 65% of the drinking-water supply sources were contaminated with faecal organisms. Thus are unfit for use in their native form. The understanding of water quality and its assessment, was poor among the sampled population. Indicating that majority of the consumers relied soly on physical appearance of drinking-water, in estimating domestic water quality. Students should be advised on simple steps that can be taken to rid water of contaminants. At the distribution level, it is recommended that the Framework for Safe Drinking-water (comprehensive risk assessment and risk management approach) proposed by the WHO be implemented in order to ensure the short term and long term health of the students of the University of Port Harcout.