Field trials were conducted at three localities during 2009 and 2010 to evaluate herbicides and their combination for effective weed control in carrot production localities in Republic of Macedonia. The weed population was consisted of annual spring and summer, and some perennial weeds. The weediness in all localities was relative high, and, depends of the year it ranged of 97.1 to 172.7 plants/m2. Herbicide efficacy evaluated 14 and 28 days after PRE and PRE+POST applications, was ranged of 42.1% (metolachlor PRE in 2010 in Bitola locality) to 99.5% (metolachlor + prometryn applied PRE in 2010 in Sveti Nikole locality). Efficacy of herbicides in control of prevailing weeds during the 2 years field trial period 14 and 28 days after PRE and PRE+POST applications was ranged between 44% and 100% in all localities. Particularly high efficacy showed combinations metolachlor + prometryn and metolachlor + linuron, respectively applied PRE which provided nearly 100% control. All applied herbicides and their combinations, except metribuzin POST showed high selectivity to carrots. Yields of the herbicides treatments reflected their efficiencies in weed control.