The human papillomavirus is the cause of cervical cancer in the great majority of cases. In a wider context, epidemiological studies have pointed to the fact that both HPV genital infection and cervical cancer strongly correlate with sexual behavior indicators. The diagnosis of gynecological cancer or of common premalignant lesions may have a deep impact on sexuality, affecting aspects of female identity. The diagnosis of genital infection by HPV negatively influenced the practices of anal and oral sex but led to a small increment in condom use.There was a reduction in sexual desire and excitement and in the quantity of orgasms. The participants carrying genital warts were the most sexually satisfied.