Humanization is a cross-sectional phenomenon that affects all structures and forms of the functioning of a socio-economic formation. It is a counterpoint to black zones in economy, egoism, aggression, pursuit of profit at any cost, etc.. In this context, we can therefore talk now about the humanization of the economy as a catalyst that eliminates immoral and unethical processes in the economy and society, supports efficient sustainable economic and social development, and not the boundless pursuit of profit, but a man and the society as a whole are in the center of its attention. We can say that a professional insight into further development shows the need to theoretically and practically develop the humanization of the economy and society in the 21st century. It is a long-term process, hence it can not be perceived as a certain status quo.