A VCT Pamphlet was developed and tested for effectiveness in changing knowledge and attitude of high school students towards VCT in North Shoa Zone, Oromia Region, Ethiopia. It was also aimed at assessing factors associated with the change in knowledge or attitude towards VCT. Randomized Controlled Trial was conducted to test the effectiveness of a VCT pamphlet in changing knowledge and attitude of high school students towards VCT. The intervention and control groups were selected randomly from the two high schools found in North Shoa. Single blinding was employed to avoid the Hawthorn Effect. The VCT pamphlet was given only to the intervention group. The pre-and post-intervention knowledge and attitude of students towards VCT were assessed by the use of structured and pre-tested self-administered questionnaire. The study shows that it is possible to change the knowledge of the target group through distributing pamphlet. It is recommended to consider different factors such as socio-demographic, knowledge and attitude level of the audience before preparation and distribution of pamphlet to attain the intended change.