The study on the impact of HIV/AIDS on the livestock-producing communities of Uganda was carried out in Kashumba and Moyo sub counties. There was no clear data that supported the impact of HIV/AIDS on livestock producing communities on labour, decision-making, grazing and watering time and factors that aggravated its effects. Data were collected using semi-structured questionnaire,focus group discussion, observation guides and review of secondary data. The study showed that there was reduction in the availability of labour for grazing and watering livestock in both Moyo and Kashumba; There was shift in decision-making and implementation from ailing household heads to selected household members. There was significant negative changes in livestock grazing and sale of livestock products in households affected by HIV/AIDS compared to those non affected. Furthermore, there was reduction in grazing and watering time for livestock activities. It was observed that daily animal source foods reduced in the affected households. The study recommended that HIV/AIDS mitigation measures be intergrated in the livestock sector plans that will create HIV/AIDS competent communities in Uganda.