The size of the population in proportion to the food production is highly relevant in the level of development of a nation, as it has a direct bearing on the quality of life of the inhabitants. As the population of the Rajshahi division in Bangladesh grows rapidly and its trend varies regionally, it is important for the socio-economic planning purposes for a region to follow the regional trends of the dynamics of population and food production, both in space and through time. Considering the spatio-temporal dynamics and distinctiveness, the relationship between population growth and food supply in the Rajshahi division deserves special investigation. The Rajshahi division is situated in the north western corner of the Bangladesh facing various natural calamities like drought, frequent flood, river bank erosion etc. The population of Rajshahi division was increased at high rate during 1974, 1981 and 1991 and it was decreased in 2001. The food grain requirement is increased as well as population growth. It increased at 76.39 percent in the last 25 years. The food production was almost doubled in 2007-08 than the year of 1981-82.