There are many issues that increase the complexity of health care today. Among these issues are (a) the cost of health care, (b) the quality of health care, (c) medical errors and patient injury, and (d) the shortage of nursing staff to care for the patients. There are drivers in place to overhaul the health care system. The drivers demand improvement in quality of care, reduction in medical errors and patient injury, improved patient health care outcomes, and a decrease in medical care expenditures. The key to addressing these issues lies within the transformation of the current hierarchical structure of the acute care unit into a High Performing Organization (HPO). This paper examines an evidence-based practice proposal utilizing Blanchard’s HPO model as a means to delineate the factors that impede high level functioning on an acute care unit, remove the barriers that obstruct high performance, and empower the staff in order to become a high performing unit (Blanchard, 2007). Leaders of high performing organizations partner with their employees in order to create an organization that is grounded in becoming high performing.