Optimal adherence to immunosuppressants in renal transplant patients is vital for the survival of the transplanted kidney. Pharmacists are in an ideal position to counsel and support patients on adherence to medication and should be actively involved in the multidisciplinary healthcare team providing patient care, specifically medication taking. The aim of this study was to assess whether a pharmacist led adherence enhancing intervention involving structured counselling and providing adherence tools such as diary cards and pillboxes, improved adherence to immunosuppressive therapy in renal transplant patients.This study indicates the need for further research into this area especially in the measurement of adherence. New more accurate methods for measuring adherence are required. The pharmacist''s role could also be improved by educating pharmacists at undergraduate level about the importance of adherence and including it in the training of all aspects of patient care, and providing information and support via continuing education to pharmacists already working in the profession.