☰ Category

In Silico Determination of Methylated Residues in Mammalian Proteins


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days


Check Your Delivery Options

Product Out of Stock Subscription

(Notify me when this product is back in stock)

Rs. 3,651

Availability: Out of stock

  • Product Description

Bioinformatics is a helpful tool to experimental studies. It is less time consuming and may provide a platform for experimental work. Post translational modification is investigated in silico, with the help of the bioinformatics tool MAPRes. This tool mines association pattern around a modified residue. In this work association rules were mined around methylated Lys/Arg residues in protein. These rules show highest preference for Gly in modified protein Arg and Ser and Gln in modified protein Lys. 75% data support the preference of Gly in methylated Arg with 100% confidence level. 25% data support the preference of Ser and Gln in methylated Lys with 100% confidence level. The comparison of MAPRes analysis results for predicted Lys and predicted Arg substrate sites with those of MeMo, MASA and BPB-MMS prediction methods show a high conformity level, ranging from 13% to 72%. This high rate of conformity points to the accuracy of the algorithm and the technique of data mining applied in MAPRes. This work will be helpful for determining methyltransferases sequence specificity in protein which will be helpful in disease such as cancer, diabetes, spinal muscular atrophy etc.

Product Specifications
SKU :COC50281
AuthorAnila Saeed,Afshan Kaleem and Hania Ramzan
Number of Pages88
Publishing Year2012-05-18T00:00:00.000
Edition1 st
Book TypeZoology: Vertebrates
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-06-08 00:00:00
0 Review(s)