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In-situ studies of protein-resistant self-assembling monolayers


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  • Product Description

Oligo(ethylene glycol) (OEG) SAMs are important tools in medical applications to hinder the irreversible adsorption of proteins on surfaces. They can be used to structure cells on surfaces or in combination with specific headgroups as sensor elements. The aim of this work was the in-situ characterization of hexa(ethylene glycol) self-assembling monolayers (SAMs), their structural changes at elevated temperatures and their longtime stability. The focus was on the interaction of the thiol molecules with the surrounding water molecules and the conformational and structural consequences. A key to the understanding of the mechanism of protein resistance is the ability of OEG-SAMs to bind water molecules at their surface and in their interior. Infrared spectroscopy is a well suited technique for the identification of molecules and their structural changes due to the interaction with their environment. The surface sensitive polarization modulation infrared reflection absorption spectroscopy (PMIRRAS) technique enables in combination with a thin liquid layer cell measurements under aqueous conditions (in-situ) with a very high signal-to-noise ratio.

Product Specifications
SKU :COC10517
AuthorStefan Zorn
Number of Pages160
Publishing Year12/21/2010
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandSüdwestdeutscher Verlag für Hochschulschriften
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-23 00:00:00