Indazole, Pyrazole and s-Triazine derivatives possess Therapeutic and Pharmaceutical activity such as anti-inflammatory, anti-pyretic, anti-parasitic, anti-malarial, anti-bacterial and anti-fungal. In this book, we have reported how to synthesize compounds bearing Indazole, Pyrazole and s-Triazine. All the new reported compounds were characterized by elemental analysis, FT-IR, 1H NMR and Mass Spectroscopy. These compounds were found to be very good anti-bacterial and anti-fungal activity. This book is useful for any reserchers of Chemistry, Pharmacy or related disciplines who are familiar with synthesis of organic derivatives.