Indigenous knowledge is the local knowledge that is unique to a given culture or society. It is used at the local level for decisions related with agriculture and household products protection, human health, natural resources management and other vital activities. However, today many of these indigenous knowledge and techniques are at risk of extinction because of the rapidly changing natural environments and fast increase in socioeconomic and political changes on a global scale. Most indigenous knowledge that used for pest managements are mostly cost effective and environment friendly unlike chemical pesticides. Thus indigenous knowledge and techniques needs to be identified, standardized, adapted, adopted and produced in the large-scale. In view of this, the book enlightens the current collected information from Dire Dawa Administration (Eastern Ethiopia) on key pest animals and indigenous knowledge and techniques used for these pests'' management. Particularly, in the book the socioeconomic background of local community, the type of key pest animals and products damaged by them and indigenous knowledge and techniques used for these pests management were presented in detail.