This study focuses attention on the information needs and information seeking behavior of the media practitioners (MPs) in Karachi. MPs are the staff members of mass media i.e. radio, television and newspaper involved in professional activities. Questionnaire-based survey method was adopted for the study. Sample Consists of 185 MPs selected randomly from four media houses i.e. radio,television, and newspaper / news agencies. For analysis of data, sampled participants were grouped into five categories i.e.1. Complete Sample 2 Media house wise i.e.television, radio and newspapers / news agencies 3rd Policy makers, policy executors and Works 4 Participants working in fields, on desks and those who work on both and fifth according to beats.Results Indicate reports are used most often. MPs require selective information. Priority.Priority of nformation is very high among all groups.Information seeking behavior of the practitioners involved in research-based programs was found to be very distinct than others.The results would be helpful for library planning,collection development and designing of library media services in house libraries.