This book aims to identify the impact of information security management on the effectiveness of applying e-management in the Governmental Organizations in Gaza. The research used the analytical descriptive approach and the comprehensive survey to collect the data in order to meet research objectives using the Statistical Package for the Social Sciences (SPSS). Questionnaires were distributed as a tool to explore the opinions of the study population, the collected questionnaires were (144), represent response rate (91.14%). Ten fields of information security management were investigated at (8) Governmental Organizations along with the effectiveness of applying e-management. The ten fields of information security management include: Security Policy, Organizational Security, Assets Classification and Control, Personnel Security, Physical and Environmental Security, Computer and Network Management, System Access Control, System Development and Maintenance, Business Continuity Planning, Compliance to Legal Requirements.