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Insights into Candida tropicalis virulence factors

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Candida tropicalis is a common species related to nosocomial infections, namely candidemia and candiduria. Several virulence factors seem to be responsible for C. tropicalis infections, which present high potential for dissemination and mortality. Adhesion to surfaces (medical devices and host cells) and biofilm formation, are considered important factors that contribute to the development of candidosis. Further, adhesion and invasion of host cells by C. tropicalis is considered the first step to initiate systemic infections. Once adhered to epithelium, C. tropicalis are able to secrete hydrolytic enzymes that cause damage in host cells membrane integrity, leading to dysfunction or disruption of host structures. Thus, the main aim of this work was to characterize the virulence factors of C. tropicalis as well as to evaluate adhesion to biotic and abiotic surfaces, biofilm formation, expression of hydrolytic enzymes and antifungal susceptibility of C. tropicalis clinical isolates from urine and blood cultures and from central venous catheters.

Product Specifications
SKU :COC100816
AuthorMelyssa Negri,Ros rio Oliveira and Mariana Henriques
LanguageEnglish
BindingPaperback
Number of Pages144
Publishing Year2011-12-05T00:00:00.000
ISBN978-3846596005
Edition1 st
Book TypeMicrobiology (non-medical)
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00
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