In this book, we show the results previously published in international scientist journals. Use of lysimeters allows for integral studies of pesticide and nutrients behavior in soil. In studies at semi- field scale it is possible to incorporate aspects related to crop such as crop development, fertilization, crop sequence, method of water supply, cultivation systems. The study was conducted during the maize crop production in plots with lysimeters in two characteristic profiles of the central region of Argentina, maintaining regional use strategies and management. By means of this comprehensive reserch the atrazine behaviour and N leaching were studied considering different factors: edaphic, climate and crop sequence and tillage system.