The use of Information and communication technology (ICT) has been increasing worldwide for teaching of science in secondary schools. Also in Pakistan, ICT technologies are now applied in a number of the Private schools and the public sector intends to use it for teaching and learning. The review of research studies suggest that appropriate and effective use of ICTs technology enhances and adds value to students? learning in science education. However, the existing use of ICTs in schools in Pakistan appears not to be up to the level of its capacity, consequently a limited impact on students? learning. Teachers are central to the successful use of ICT resources in science teaching and any use successful integration depends on the teachers comfort level with its use. Therefore, exploring their perceptions and practices of integrating ICTs with teaching of science would help in understanding the existing situation, of ICTs use in schools, so that planning for integration may be made.