Frequency spectrum has become a rare resource these days; another mean is to be looked after to improve the existing wireless technology. Which gives rise to concept of Heterogeneous Network. So, LTE-A employs Heterogeneous Network which consist of several Low power nodes within one High power node. In this book, Macro eNB is a High power node and Femto eNB is a low power node. Chances of occurance of Intercell interference is high when the user is at the edge of the cell. This book focus on the interference due to the Macro eNB to the cell edge user of Femto eNB . 3GPP LTE-A Enhanced Inter-Cell Interference Coordination (eICIC) scheme has proposed Almost Blank Sub-frame (ABS) as a solution towards the intercell interference. The eICIC is able to remove the interference towards the data signal of the corresponding sub-frames of the co-channel victim Femto eNB with the help of Almost Blank Sub-frame (ABS). However, even with the usages of ABS, interference from CRSs and other physical signals still appears. This book has discussed the methodology to reduce the interference due to the collision of reference signal and demonstrated Matlab simulation results.