Your body uses glucosamine, a natural compound, to stimulate your cells to create one of the main building blocks of joint cartilage -proteoglycans.As you age, the amount of glucosamine created by your body decreases. The result? Your cartilage and bones begin to scrape against each other, your joints become damaged, and the lubricating synovial fluid in your joint spaces becomes thin and watery. To ensure effective absorption and tissue utilization, it's highly recommended that one takes glucosamine in the sulfate form. This is the way glucosamine is found in the body.Chondroitin sulfate attracts and holds large amounts of water to the cartilage-building proteoglycan molecules. Since cartilage has no blood supply, this fluid is necessary to nourish and lubricate joints. All supplements are packaged in HDPE (High Density Polyethylene) bottles. These bottles keep moisture vapor out, protecting the freshness and integrity of their contents.