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Kupffer Cell Depletion in the SCID-uPA Chimeric Mouse Model


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

The SCID/uPA mouse model is a valuable tool for the study of human hepatic diseases and functions. This model may also shed light on the nature, and solutions to, xenograft rejection. The variability in the level of human chimerism achieved in this model warrants further investigation and improvement.Macrophage depletion may improve chimerism in this model. We hypothesized that Kupffer Cell (KC) depletion would enhance chimerism. Our results uncovered the dose efficacy and toxicity of clodronate liposomes in both adult SCID mice and neonatal SCID/uPA mice.

Product Specifications
SKU :COC97705
AuthorAli Cadili
Number of Pages112
Publishing Year2011-06-15T00:00:00.000
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00