This guide deals with how to establish a lab facility that contain the most important devices that correlated with genes from DNA isolation into the most sophisticated analysis that genes must to be submitted to. This handbook aims to introduce everybody who has any degree of interest in this subject into a way of constructing any platform that deals with genes. Undoubtedly, when any person reviews the instruments of such specific field, he gets a lot of benefits in his practical profession. Though in all ten chapters of this handbook the general scheme has instrumentation aspect, the basic steps of molecular biology protocols are dealt with in order to walk in parallel with their corresponding instruments. Consequently, this is an inevitable guide for all students of biotechnology and molecular biology field. When this book is read, it's possible for the reader to know the basic steps in establishing a molecular lab, platform, unit, department, or even a whole genetic facility.