Category

share

MACROPHAGE-ADIPOCYTE CROSS-TALK

MACROPHAGE-ADIPOCYTE CROSS-TALK

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

 
₹ 4,396

Availability: Out of stock

 

Delivery :

5% Cashback on all Orders paid using MobiKwik Wallet T&C

Free Krispy Kreme Voucher on all Orders paid using UltraCash Wallet T&C
Product Out of Stock Subscription

(Notify me when this product is back in stock)

  • Product Description
 

Recent studies suggest that chronic inflammation of adipose tissues with macrophage infiltration and enhanced expression of pro-inflammatory cytokines plays a significant role in the development of obesity-related metablic disorders, such as type 2 diabetes. It was demonstrated that adenovirus- mediated over-expression of adiponectin, an anti- inflammatory insulin-sensitizing adipokine with reduced expression in obesity, resulted in a marked down-regulation of several inflammation-related genes, including F4/80 and CD68 (macrophage markers), and monocyte chemotactic protein-1 (MCP- 1), in the white AT of 12 weeks old db/db diabetic mice. It was hypothesized that the reduced expression of adiponectin might play an important role in initiating macrophage-adipocyte cross-talk which leads to obesity-related insulin resistance and diabetes. This study aimed at determining the time course and magnitude of macrophage infiltration and inflammatory activation in AT, in relation to changes in the AT level of adiponectin, glucose tolerance and insulin sensitivity, in db/db diabetic mice.

Product Specifications
SKU :COC16883
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-25
0 Review(s)