Call Us 080-41656200 (Mon-Sat: 10AM-8PM)
Free Shipping above Rs. 1499
Cash On Delivery*

Macrophages innate immune responses to bacterial infections


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days


Check Your Delivery Options

Rs. 3,651

Availability: In stock

  • Product Description

Macrophages are the first line of defense against microbial pathogens; they recognize microbial structures and products via surface receptors and intracellular antigen sensors. Engagement of surface receptors results in phagocytosis of the microbe into a specialized vacuole, the phagosome. Through a series of fusogenic events, the phagosome matures into a microbicidal phagolysosome that is highly acidic and contains a number of degradative enzymes and toxic molecules that cause destruction of the microbe. Salmonella typhimurium (S. typhimurium) and Legionella pneumophila (L. pneumophila) are two pathogenic Gram-negative bacteria that are able to block phagosome maturation. The hypothesis is that the macrophages’ response to these pathogens contains a common as well as a pathogen-specific response. Genome-wide transcription profiling approach was used to compare macrophage responses to phagocytosis of S. typhimurium or L. pneumophila at early time points, 2h and 4h post-infection. This book highlights the importance of comparing the response to different bacterial infections in order to better understand the innate immunity mechanisms and should be useful for scientist in the field

Product Specifications
SKU :COC36403
AuthorKanny Diallo
Number of Pages104
Publishing Year10/31/2012
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00