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Marginal and Random effect models in Vaccine Clinical Trials

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

In many clinical trials, in order to characterize the safety profile of a subject with a given treatment, multiple measurements are taken over time. Mostly, measurements taken from the same subject are not independent. The types of model for data analysis highly depend on the nature and measurement scale of the outcome variable. In this book, the two model families: marginal, and random effect models that take the correlation among measurements of the same subject into account were briefly discussed using real datasets. In case of marginal models the correlated nature of the data is taken into account inside the estimating equation, while for random effects model it is done through the random effect part. In the random effect approach the goal is to determine subject-specific changes over the courses of the study, while in the marginal model the emphasis is to determine the overall change. Joint modeling approaches that used to model different outcomes jointly, and model selection and diagnosis measures were discussed briefly. Moreover, SAS codes used in the analysis for each model type were included in book.

Product Specifications
SKU :COC67975
AuthorBedilu Alamirie Ejigu
LanguageEnglish
BindingPaperback
Number of Pages60
Publishing Year2013-02-03T00:00:00.000
ISBN9783659329371
Edition1 st
Book TypeStochastics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-08 00:00:00