This Book is the result of my candidature for the Master of Medical Philosophy (2yr higher research degree) at the University of Sydney. In it is presented an exhaustive summary of the risk and treatment factors of squamous cell carcinoma of the lip and analysis of original data from a 27 year dataset of the Department of Radiation Oncology at Westmead Hospital, Sydney Australia. The literature review includes a comprehensive summary of treatment outcomes for lip cancer. The original data analysis employs survival analysis and the use of a novel technique known as prognostic risk modelling. This book is useful for clinicians and researchers and those with a general interest in cancer.