Microbial Fuel Cell (MFC) technology represents a multi-disciplinary approach to the quest for alternate sources of energy. It symbolizes the confluence of the chemical, physical and life sciences and is a meeting point of basic and applied research. Since clean water and stable sources of electricity are two major needs that must be addressed in the developing world. MFC is an innovative approach that convert the energy stored in chemical bonds in organic compounds to electrical energy. MFC uses microorganisms as the biocatalysts to catalyze the oxidation of organic and inorganic matter and generate current. MFC technologies are a promising and yet completely different approach to wastewater treatment as the treatment process can become a method of capturing energy in the form of electricity or hydrogen gas, rather than a drain on electrical energy.